Robust Estimation of the Proportion of Treatment Effect Explained by Surrogate Marker Information

Documentation for package ‘Rsurrogate’ version 2.0

Aug.R.s.surv.estimate	Calculates the augmented estimator of the proportion of treatment effect explained by the surrogate marker information measured at a specified time and primary outcome information up to that specified time
delta.estimate	Calculates treatment effect
delta.s.estimate	Calculates model-based or robust residual treatment effect
delta.s.surv.estimate	Calculates robust residual treatment effect accounting for surrogate marker information measured at a specified time and primary outcome information up to that specified time
delta.surv.estimate	Calculates treatment effect in a survival setting
delta.t.surv.estimate	Calculates robust residual treatment effect accounting only for primary outcome information up to a specified time
d_example	Hypothetical data
d_example_surv	Hypothetical survival data
fieller.ci	Constructs Fieller's confidence interval.
R.s.estimate	Calculates the proportion of treatment effect explained
R.s.surv.estimate	Calculates the proportion of treatment effect explained by the surrogate marker information measured at a specified time and primary outcome information up to that specified time
R.t.surv.estimate	Calculates the proportion of treatment effect explained by the primary outcome information up to a specified time