Phase I/II Adaptive Dose-Finding Design for Combination Studies

Documentation for package ‘dfcomb’ version 2.2

dfcomb-package	Phase I and Phase I/II Adaptive Dose-Finding Design for Combination Studies
CombIncrease_next	Combination determination with logistic model
CombIncrease_sim	Combination design Simulator using Logistic model
CombPlateau_next	Combination determination for the combination of two agents where toxicity is increasing with the dose of both agent and efficacy is increasing and possibly plateaus with the dose of one agent
CombPlateau_sim	Combination design Simulator for the combination of two agents where toxicity is increasing with the dose of both agent and efficacy is increasing and possibly plateaus with the dose of one agent
dfcomb	Phase I and Phase I/II Adaptive Dose-Finding Design for Combination Studies
print.CombIncrease_next	Combination determination with logistic model
print.CombIncrease_sim	Combination design Simulator using Logistic model
print.CombPlateau_next	Combination determination for the combination of two agents where toxicity is increasing with the dose of both agent and efficacy is increasing and possibly plateaus with the dose of one agent
print.CombPlateau_sim	Combination design Simulator for the combination of two agents where toxicity is increasing with the dose of both agent and efficacy is increasing and possibly plateaus with the dose of one agent