Exploring Genomic Relations for Enhanced Interpretation Through Enrichment, Similarity, Network and Annotation Analysis


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Documentation for package ‘XGR’ version 1.0.10

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eTerm Definition for S3 class 'eTerm'
ImmunoBase Immune-disease associated variants, regions and genes from ImmunoBase (hg19)
JKscience_TS2A Table S2A for cis-eQTLs among shared datasets from Benjamin et al. (2014)
print.eTerm Definition for S3 class 'eTerm'
xCheckParallel Function to check whether parallel computing should be used and how
xCircos Function to visualise a network as a circos plot
xColormap Function to define a colormap
xConverter Function to convert an object between graph classes
xDAGanno Function to generate a subgraph of a direct acyclic graph (DAG) induced by the input annotation data
xDAGpropagate Function to generate a subgraph of a direct acyclic graph (DAG) propagaged by the input annotation data
xDAGsim Function to calculate pair-wise semantic similarity between input terms based on a direct acyclic graph (DAG) with annotated data
xDefineNet Function to define a gene network
xEnrichBarplot Function to visualise enrichment results using a barplot
xEnrichCompare Function to compare enrichment results using side-by-side barplots
xEnrichConciser Function to make enrichment results conciser by removing redundant terms
xEnrichDAGplot Function to visualise enrichment results using a direct acyclic graph (DAG)
xEnrichDAGplotAdv Function to visualise comparative enrichment results using a direct acyclic graph (DAG)
xEnricher Function to conduct enrichment analysis given the input data and the ontology and its annotation
xEnricherGenes Function to conduct enrichment analysis given a list of genes and the ontology in query
xEnricherSNPs Function to conduct enrichment analysis given a list of SNPs and the ontology in query
xEnricherYours Function to conduct enrichment analysis given YOUR own input data
xEnrichNetplot Function to visualise enrichment results using different network layouts
xEnrichViewer Function to view enrichment results
xFunArgs Function to assign (and evaluate) arguments with default values for a given function
xGR Function to create a GRanges object given a list of genomic regions
xGR2GeneScores Function to identify likely modulated seed genes given a list of genomic regions together with the significance level
xGR2nGenes Function to define nearby genes given a list of genomic regions
xGRsampling Function to generate random samples for data genomic regions from background genomic regions
xGRscores Function to score genomic regions based on the given significance level
xGRviaGeneAnno Function to conduct region-based enrichment analysis using nearby gene annotations
xGRviaGenomicAnno Function to conduct region-based enrichment analysis using genomic annotations via binomial test
xGRviaGenomicAnnoAdv Function to conduct region-based enrichment analysis using genomic annotations via sampling
xLiftOver Function to lift genomic intervals from one genome build to another.
xRd2HTML Function to convert Rd files to HTML files
xRDataLoader Function to load the package built-in RData
xRdWrap Function to wrap texts from Rd files
xSM2DF Function to create a data frame (with three columns) from a (sparse) matrix
xSNP2GeneScores Function to identify likely modulated seed genes given a list of SNPs together with the significance level (e.g. GWAS reported p-values)
xSNP2nGenes Function to define nearby genes given a list of SNPs
xSNPlocations Function to extract genomic locations given a list of SNPs
xSNPscores Function to score lead or LD SNPs based on the given significance level
xSocialiser Function to calculate pair-wise semantic similarity given the input data and the ontology and its annotation
xSocialiserDAGplot Function to draw DAG plot for visualising terms used to annotate an input SNP or gene
xSocialiserDAGplotAdv Function to draw DAG plot for comparing two sets of terms used to annotate two SNPs or genes in query
xSocialiserGenes Function to calculate pair-wise semantic similarity given a list of genes and the ontology in query
xSocialiserNetplot Function to visualise terms used to annotate an input SNP or gene using different network layouts
xSocialiserSNPs Function to calculate pair-wise semantic similarity given a list of SNPs and the ontology in query
xSparseMatrix Function to create a sparse matrix for an input file with three columns
xSubneterGenes Function to identify a subnetwork from an input network and the signficance level imposed on its nodes
xSubneterGR Function to identify a gene network from an input network given a list of genomic regions together with the significance level
xSubneterSNPs Function to identify a gene network from an input network given a list of seed SNPs together with the significance level (e.g. GWAS reported p-values)
xSymbol2GeneID Function to convert gene symbols to entrez geneid
xVisInterp Function to visualise interpolated irregular data
xVisKernels Function to visualise distance kernel functions
xVisNet Function to visualise a graph object of class "igraph"