Self Contained Gene Set Analysis for Gene- And Pathway-Environment Interaction Analysis


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Documentation for package ‘PIGE’ version 1.1

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PIGE-package Gene and pathway p-values using the Adaptive Rank Truncated Product test
ARTP.GE Gene and pathway p-values using ARTP method
bootstrap.snp Parallel computing of the Likelihhod ratio test (or Wald test) for an interaction term (or a simple SNP effect) on bootstrap sample
compute.p.snp.obs Likelihhod ratio test (or Wald test) for an interaction term (or a single SNP effect)
data.pathway Fictive data frame corresponding to the gene x pathway analysis for the example of case-control study.
data.pathway.surv Fictive data frame corresponding to the gene x pathway analysis for the example of survival analysis.
data.pige Sample data of a case-control study
data.surv Fictive data set for sample data of a survival analysis.
data.to.list.gene.snp Annotation gene/SNP
data.to.PIGE Generate data for Gene- and Pathway-environment interaction
list.gene.snp Fictive list for the case-control study example containing the names of the snp for each gene included in the studied pathways
list.gene.snp.surv Fictive list (for survival example) containing the names of the snp for each gene included in the studied pathways
LR.cont Wald test for an adjusted model.
LR.cont.boot Wald test for an adjusted model.
LR.cont.surv Wald test for an adjusted model.
LR.inter.cat Likelihhod ratio test for an interaction term
LR.inter.cat.boot Likelihhod ratio test for an interaction term
LR.inter.cat.surv Likelihhod ratio test for an interaction term
LR.inter.cont Wald test for an interaction term
LR.inter.cont.boot Wald test for an interaction term
LR.inter.cont.surv Wald test for an interaction term
permutation.snp Parallel computing of the Likelihhod ratio test (or Wald test) for an interaction term (or a simple SNP effect) on permutation sample
PIGE Gene and pathway p-values using the Adaptive Rank Truncated Product test
snp.gene.select Fictive data frame containing the names of the gene (first column) and the names of the SNP belonging to the SNPS (second column)